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It’s time to rejuvenate your liver

It’s time to rejuvenate your liver

How often do you take your liver for granted? What we eat and how we live our lives do affect liver health, even without us noticing. The liver is the main detoxification hub in our body, therefore it is important look after our liver and increase our awareness of liver disease to treat it before it is too late.

Some possible symptoms of poor liver health include frequent fatigue, jaundice, fluid retention at lower extremities, skin over-sensitivity, and such. A fatty liver may develop without any noticeable symptoms in the early stages. Fatty liver is diagnosed when there is 5% or more of fat in the liver.

Simultaneously, free radicals will attack the phospholipid bilayer, causing damage. Phospholipids are the building blocks of cell membranes, therefore the body requires a constant supply to repair damaged liver cell membrane.

liver

A fatty liver may develop without any noticeable symptoms in the early stages.

The phospholipids layer is very important as it is the structural make up of liver cell membrane, and encloses cytoplasm and other contents of a cell. Among all types of phospholipids, phosphatidylcholine (PC) is the most abundant that make up the liver cell membrane.

PC is vital in maintaining the shape of the membrane and needed for proper functioning of liver cells. Damage to the liver cell membrane has been shown to affect liver homeostasis, liver damage, and the recovery process of the liver.[1]

Dietary supplement of the PC at 900mg daily for three months has shown to improve the liver conditions of people diagnosed with fatty liver, liver fibrosis, hepatitis, and even alcoholic cirrhosis.[2]

Besides phospholipids, B vitamins are also very important in supporting a healthy liver. B vitamins are often found deficient in people with liver diseases. Furthermore, B vitamins are needed as co-factor to release energy from foods consumed.

For instance, the fats we take in require B vitamins for metabolism to generate energy, so the large fat molecules will not continuously deposit in liver cell membranes.

liver

Free radicals will attack the phospholipid bilayer, causing damage.

In addition, B vitamins are involved in glutathione production, which is important in detoxification. Glutathione is an internal source of antioxidant combating free radicals and facilitates elimination of xenobiotics (e.g. drugs, medication, pollutants).[4]

Vitamin E, on the other hand, is an important antioxidant in the cell antioxidant defence system. It helps neutralise free radicals before they damage the phospholipid bilayer of the liver cell membrane.

Studies have shown that subjects who consume essential phospholipids, PC. together with B vitamins (B1, B2, B3, B6, B12) and vitamin E are able to improve their liver functions.[2][3]

The liver is the only organ that is able to regenerate and repair itself under damage. However, we need to ensure an adequate supply of the essential phospholipids for its regeneration.

Essential phospholipids with B vitamins and vitamin E have been clinically proven to improve liver functions among people with fatty liver, liver fibrosis and cirrhosis.

This information is brought to you by BiO-LiFE (Marketing) Sdn Bhd. For details, visit biolife.com.my or contact (03) 7499-7999.

References: [1] Kidd, PM, 1996. Phosphatidylcholine: A Superior Protectant Against Liver Damage. Alternative Medicine Review, 1(4):258-274. [2] Report on post marketing studies of the effectiveness of Livolin Forte – Hepatoprotector, in patients with chronic diffuse hepatic diseases by Dr MD (Medicine), Kiev Medical Academy, Ukraine. [3] Vdovychenko, VI, Denysyuk, YS, Bidyuk, ОА, Kopiy, NL, and Ferents, IM, 2006. Experience of treatment of chronic alcoholic hepatitis with Livolin Forte. Modern Gastroenterology, No.6(32):9-11. [4] Pastore A et al. 2003. Analysis of glutathione: implication in redox and detoxification. Clinica Chimica Acta. 333(1): 19-39. 

Liver issues that should not be ignored

Liver issues that should not be ignored

The liver is the largest internal organ in the body and when it is diagnosed to contain over 5% fat, then it is a fatty liver.
This means the liver is not functioning properly, as it should break down fat, not accumulate it.
Many do not think that a fatty liver is a big health issue, but according to Malaysian Liver Foundation (MLF) president Tan Sri Dr Ismail Merican, about 60% of Malaysians risk dying due to fatty liver – largely because they are unaware of or ignore the problem.

A seemingly benign condition
The risk factors for having a fatty liver include:
• alcohol consumption
• being overweight or obese
• unhealthy diet intake (food high in fat or carbohydrates)
• long-term medication use
• rapid weight loss
• exposure to chemicals, pollution or contamination
• metabolic conditions (such as Type 2 diabetes, hyperlipidemia)
• virus infection
• family history
Liver is a super worker that does not complain until almost exhausted.
Known as the silent organ, it has limited nerves, which means poor liver health rarely shows direct symptoms.
Similarly, fatty liver does not significantly affect health although its presence means you may be at risk of getting liver disease.
Fat accumulation in the liver is an early indicator of poor liver health.
The accumulated fat is prone to be oxidised by free radicals, which causes eventual damage, and inflammation of liver cell membranes, which progresses to chronic liver condition.

Fatty liver, liver health, Bio-Life, Star2.com

Healthy liver (left) versus fatty liver (right, with damaged membrane and inflammation).

Do not procrastinate
Liver cell membranes consist of bilayer phospholipids, which are vital for maintaining cell structure and function as they are the main building blocks for the cell membrane.
Damaged liver cell membranes indicate missing parts of the phospholipids bilayer, just like lost puzzle pieces.
Replenishing essential phospholipids is crucial as it repairs and regenerates healthy liver cells.
You also need to boost the liver’s metabolism to enhance the breaking-down process of excess fat layer and detoxification.
Nutrients your liver need to support a healing process and protect it from further damage include:
• Essential phospholipids
> solely phosphatidylcholine (a type of phospholipid that makes up 85% of liver cell membranes) isolated from soybeans
> the “regenerator” facilitates damaged liver cell membrane repair and healthy liver cell regeneration
• B vitamins
> Vitamins B1, B2, B3, B6 and B12
> the “detoxifier” improves metabolism, which assists in breaking down excess fat for energy, and detoxification
• Vitamin E
> vitamin with potent antioxidant properties
> the “protector” helps minimise further damage caused by free radicals and oxidative stress

This health information is brought to you by BiO-LiFE Marketing Sdn Bhd. For details, contact 03-7499 7999 or visit this webpage.

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